منابع مشابه
Remote ischemic per-conditioning: a novel therapy for acute stroke?
BACKGROUND AND PURPOSE Remote ischemic preconditioning is a phenomenon by which a short period of sublethal ischemia to an organ protects against subsequent ischemia in another organ. We have recently demonstrated that remote ischemic conditioning by transient hind limb ischemia delivered during ischemia and before reperfusion can provide potent cardioprotection, a phenomenon we termed per-cond...
متن کاملEndovascular Therapy for Ischemic Stroke
The utility of intravenous tissue plasminogen activator (IV t-PA) in improving the clinical outcomes after acute ischemic stroke has been well demonstrated in past clinical trials. Though multiple initial small series of endovascular stroke therapy had shown good outcomes as compared to IV t-PA, a similar beneficial effect had not been translated in multiple randomized clinical trials of endova...
متن کاملAntithrombotic and thrombolytic therapy for ischemic stroke.
Thrombolytic and antithrombotic agents form the cornerstone of stroke treatment and prevention. Recombinant tissue plasminogen activation (rt-PA) improves the outcome in patients treated within 3 hours of stroke onset. The risk-benefit ratio is narrow because of an increased risk for bleeding, but studies do not support a higher risk in the geriatric population. Emerging trials are directed at ...
متن کاملAntithrombotic and Thrombolytic Therapy for Ischemic Stroke
Abbreviations: ACE 5 ASA and Carotid Endarterectomy; BI 5 Barthel Index; CAPRIE 5 Clopidogrel vs Aspirin in Patients at Risk of Ischemic Events; CAST 5 Chinese Acute Stroke Trial; CI 5 confidence interval; CVST 5 cerebral venous sinus thrombosis; DVT 5 deep venous thrombosis; ECASS 5 European Cooperative Acute Stroke Study; ESPS 5 European Stroke Prevention Study; FDA 5 Food and Drug Administra...
متن کاملAntithrombotic and Thrombolytic Therapy for Ischemic Stroke
Objectives: This article provides recommendations on the use of antithrombotic therapy in patients with stroke or transient ischemic attack (TIA). Methods: We generated treatment recommendations (Grade 1) and suggestions (Grade 2) based on high (A), moderate (B), and low (C) quality evidence. Results: In patients with acute ischemic stroke, we recommend IV recombinant tissue plasminogen activat...
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ژورنال
عنوان ژورنال: Neurosurgery
سال: 2012
ISSN: 0148-396X
DOI: 10.1227/01.neu.0000413220.21264.df